Complete Nucleotide Sequence of the pCTX-M3 Plasmid and Its Involvement in Spread of the Extended-Spectrum -Lactamase Gene blaCTX-M-3
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چکیده
Complete Nucleotide Sequence of the pCTX-M3 Plasmid and Its Involvement in Spread of the Extended-Spectrum -Lactamase Gene blaCTX-M-3 M. Gołębiewski,† I. Kern-Zdanowicz,* M. Zienkiewicz,‡ M. Adamczyk, J. Żyliǹska, A. Baraniak, M. Gniadkowski, J. Bardowski, and P. Cegłowski Department of Microbial Biochemistry, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, and National Medicines Institute, Warsaw, Poland
منابع مشابه
Complete nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum beta-lactamase gene blaCTX-M-3.
Here we report the nucleotide sequence of pCTX-M3, a highly conjugative plasmid that is responsible for the extensive spread of the gene coding for the CTX-M-3 extended-spectrum beta-lactamase in clinical populations of the family Enterobacteriaceae in Poland. The plasmid belongs to the IncL/M incompatibility group, is 89,468 bp in size, and carries 103 putative genes. Besides bla(CTX-M-3), it ...
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1. Galimand M, Courvalin P, Lambert T. Plasmid-mediated highlevel resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother 2003; 47: 2565–71. 2. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88–94. 3. Bogaerts P, Galimand M, Bauraing C et al. Emergence of ArmA ...
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